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Moderna, Inc. (MRNA) CEO Stéphane Bancel Presents at NASDAQ 43rd Virtual Investor Conference (Transcript

We've got quite a number of calls in the last few weeks once data got out, but still I would say – I think the U.S. has done the best job that I have seen, and I've not talked to every country in the world.

So I guess that leads to the other question, which is you've set a bar in terms of supply 500 million to 1 billion doses for next year.

We will not have been able to fund $1 billion to run the 30,000 people for Phase III study if the U.S. government had not helped us.

So let me start at the starting point, which is – on Monday, we filed the same data to all the key regulatory agencies around the world, so U.S., Canada, UK, Europe, Switzerland, Singapore, Israel, and WHO.

You know, given we've done all the studies in the U.S. FDA has seen preclinical models, challenge models, Phase I, Phase II data.

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Image of article 'We Still Don’t Know The Full Extent Of How This Wave Of The Coronavirus Is Impacting People Of Color'

We Still Don’t Know The Full Extent Of How This Wave Of The Coronavirus Is Impacting People Of Color

Yet there continued to be inadequate case data to determine the full effect of the pandemic as it moved into rural states with larger white populations, like North Dakota, South Dakota, Wyoming, Iowa, and Nebraska.

In North Dakota, about 37% of cases were of unknown race “due to that field not being completed during testing and/or by the individuals refusing to report,” according to Grace Njau, director of special projects and health analytics at the North Dakota Department of Health.

While racial data about people who have died from COVID-19 was not available in North Dakota at the time of publication, Leingang told BuzzFeed News she has observed a clearer disparity in outcomes, especially among Native American patients who test positive for COVID-19.

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Image of article 'Intra-Cellular Therapies: Another Growth Cycle Approaching (NASDAQ:ITCI'

Intra-Cellular Therapies: Another Growth Cycle Approaching (NASDAQ:ITCI

At this point in its life cycle, the main concern for Intra-Cellular is if Caplyta will continue to gain strong sales traction.

Leveraging positive data for both Study 402 and Study 404, you can expect approval of Caplyta for BPD.

Despite the rampaging effects of COVID-19, Intra-Cellular delivered impressive Caplyta quarterly sales.

Given the messengers' importance, you can see why Intra-Cellular is assessing Caplyta's use to alleviate the suffering in schizophrenia, bipolar depression (BPD), major depressive disorder ("MDD"), sleep, and behavioral disturbances as shown above.

After a magnificent performance last year with Caplyta approval for schizophrenia, Intra-Cellular stocks gave up some gains.

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As hospitals cope with a COVID-19 surge, cyber threats loom

And it's part of why cybercriminals have focused their attention on health care organizations — especially now, as hospitals across the country are coping with a surge of COVID-19 patients, he said.

Over the course of 2020, many hospitals postponed technology upgrades or cybersecurity training that would help protect them from the newest wave of attacks, said health care security consultant Nick Culbertson.

The same day as UVM's attack, the FBI and two federal agencies warned cybercriminals were ramping up efforts to steal data and disrupt services across the health care sector.

The Vermont hospital had fallen prey to a cyberattack, becoming one of the most recent and visible examples of a wave of digital assaults taking U.S. health care providers hostage as COVID-19 cases surge nationwide.

Employees lost access to databases, digital health records, scheduling systems and other online tools they rely on for patient care.

Image of article 'Skin Oncology Firm MedC Biopharma Launches Private Placement Offering on DealSquare'

Skin Oncology Firm MedC Biopharma Launches Private Placement Offering on DealSquare

DealMaker makes private placement transactions surprisingly pleasant, delivering speed, innovation, and efficiency to the global private capital markets.

To view MedC Biopharma’s private placement offering on DealSquare, click here.

Connect with DealSquare: Website| LinkedIn | Twitter About DealMaker DealMaker is an innovative cloud-based platform for the capital raising and settlement of domestic and international private placements in capital markets, KYC and Fund Formation.

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Image of article 'World War II veteran beats Covid    -    19, marks 104th birthday'

World War II veteran beats Covid - 19, marks 104th birthday

For Wooten's birthday, a company erected a yard display that included the Alabama athletics logo, a cake, candles and a patriotic hat.

Wooten, a big University of Alabama football fan, received a video phone call from Alabama coach Nick Saban after that scare got attention on the local news, she said.

BIRMINGHAM: An Alabama man who spent World War II repairing bomb-damaged trains in France recovered from a fight with Covid-19 in time to mark his 104th birthday on Thursday.

Image of article 'Identifying markers of COVID-19 infection using blood tests'

Identifying markers of COVID-19 infection using blood tests

Evaluation of Routine Blood Tests for Diagnosis of Suspected Coronavirus Disease 2019, Clinical Laboratory (2020).

These laboratory criteria, combined with medical history and imaging tests, can be very useful to screen patients with suspected COVID-19.

The researchers behind the study have established six criteria linked to suspected COVID-19 infection using the blood lymphocyte and eosinophil count, and the levels of ferritin, lactate dehydrogenase, C-reactive protein and d-dimer in plasma.

The Laboratory of the Virgen del Rocío University Hospital in Seville has identified the values of six biochemical biomarkers which indicate the patient may be infected with the coronavirus.

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Image of article 'Immunity passports: Ethical conflict and opportunity'

Immunity passports: Ethical conflict and opportunity

Credit: University of the Basque Country Immunity passports are a means of registering whether an individual has developed immunity to COVID-19 and is therefore unlikely to either catch or spread the disease.

Immunity passports, fundamental rights and public health hazards: a reply to Brown et al, Journal of Medical Ethics (2020).

However, if there are not enough vaccines for everyone at that time, what we will be doing is recognizing the validity and moral admissibility of immunity passports, at least in terms of fundamental rights."

If a person does not pose a threat to public health because they cannot spread the infection, then their right to freedom of movement should be respected, regardless of how they acquired that immunity.

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Image of article 'COVID-19 pandemic responsible for decrease in hepatitis C testing'

COVID-19 pandemic responsible for decrease in hepatitis C testing

Sperring et al, Impact of the 2020 COVID-19 Pandemic on Ambulatory Hepatitis C Testing, Journal of Primary Care Community Health (2020).

HCV test results for patients were collected each day and comparisons were made for all testing across the hospital, as well as exclusively for the primary care sites that have been the most heavily affected by the introduction of telemedicine.

Published in the Journal of Primary Care and Community Health, this new research highlights the impact that the COVID-19 pandemic is having on hospital-wide and ambulatory HCV testing, and the ramifications of this decrease in identification of the virus.

New research from Boston Medical Center finds that the COVID-19 emergency systemic changes made to decrease in-person visits during the pandemic have led to a decrease in hospital-wide Hepatitis C (HCV) testing by 50 percent, and a reduction in new HCV diagnoses by more than 60 percent.

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Image of article 'Antiviral drugs have no effect on mortality in COVID-19'

Antiviral drugs have no effect on mortality in COVID-19

(HealthDay)—For hospitalized patients with COVID-19, remdesivir, hydroxychloroquine, lopinavir, and interferon regimens seem to have little to no effect on mortality, according to a study published online Dec. 2 in the New England Journal of Medicine.

Hongchao Pan, Ph.D., from the University of Oxford in the United Kingdom, and colleagues examined in-hospital mortality in four pairwise comparisons of each of four trial drugs (remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a) and its control among inpatients with COVID-19.

None of the trial drugs reduced in-hospital mortality, initiation of ventilation, or duration of hospitalization.

"The unpromising overall findings from the regimens tested suffice to refute early hopes, based on smaller or nonrandomized studies, that any of these regimens will substantially reduce inpatient mortality, the initiation of mechanical ventilation, or hospitalization duration," the authors write.

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Image of article 'Biden will ask Americans to wear masks for 100 days'

Biden will ask Americans to wear masks for 100 days

As for Fauci, Biden made it clear that the nation's top infectious diseases expert would be a central player in the U.S. coronavirus response, The New York Times reported.

Britain First to Approve Emergency Use of Pfizer's COVID vaccine Britain became the first Western country to allow emergency use of a coronavirus vaccine on Wednesday, approving Pfizer's candidate in the race to inoculate millions of people around the globe.

Though Britain has an early jump on distribution of the Pfizer vaccine, it will have no effect on the distribution of the hundreds of millions of doses that other wealthy countries like the United States have bought in prepaid contracts, the Times said.

In the United States, an advisory panel on Tuesday approved a vaccine distribution plan that recommends health care workers and nursing home residents and staff be the first to receive any approved coronavirus vaccine.

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Image of article 'How safe are the new COVID-19 vaccines'

How safe are the new COVID-19 vaccines

Offit added, "What you're going to be able to say now, when these vaccines roll out, is you're going to be able to say that, at least in tens of thousands of people, there were no uncommon serious side effects that were seen within two months of getting a dose."

'Very reassured' Offit said skyscraper-high reams of documents tend to be generated during clinical trials, and the FDA advisory board painstakingly reviews all that data before recommending vaccine approval.

Offit is a member of the U.S. Food and Drug Administration advisory board that will review the clinical trial data for both the Pfizer and Moderna vaccines within the next two weeks.

Average folks can take comfort from the safety data that's already been gathered in clinical trials, and additional data expected to pour in from millions more people participating in the earliest waves of COVID-19 vaccine distribution, said Dr. Paul Offit.

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Image of article 'The best kids' snow boots in 2020'

The best kids' snow boots in 2020

To navigate the hundreds of different kids' winter boots out there, we asked the parents who have challenged their families to spend 1,000 hours outside — a goal that requires going out in every season — to share their favorite kids' snow boots.

Kids' snow boots should be warm, waterproof, easy to put on, and flexible.

Bogs Classics are the best kids' snow boots we've tried so far because of the waterproof, slip-on design and warm lightweight neoprene insulation.

A good pair of snow boots is essential to winter outdoor play, but boots are some of the trickiest types of footwear to buy for children.

Age complicates the selection even further: Toddlers don't walk well in heavy footwear, while school-aged children often have to put snow boots on and take them off quickly for recess.

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Citius Pharmaceuticals To Present Corporate Update At Benzinga Global Small Cap Conference On December 8

Such statements are made based on our expectations and beliefs concerning future events impacting Citius.

Mr. Mazur will discuss recent Company developments for these product candidates including: Citius is a late-stage specialty pharmaceutical company dedicated to the development and commercialization of critical care products, with a focus on anti-infectives and cancer care.

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Citius Pharmaceuticals to Present Corporate Update at Global Small Cap Conference on December 8

Citius is a late-stage specialty pharmaceutical company dedicated to the development and commercialization of critical care products, with a focus on anti-infectives and cancer care.

Submission of a pre-investigational new drug (PIND) consultation request for Mino-Wrap with written response and guidance is expected Update on Halo-Lido which is anticipated to begin Phase 2b trial in the first quarter of 2021 About Citius Pharmaceuticals, Inc.

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Image of article 'COVID-19 vaccine efficacy depends on distribution, public confidence, experts say'

COVID-19 vaccine efficacy depends on distribution, public confidence, experts say

Although clinical trials to date indicate both the Pfizer and Moderna vaccines are up to 95% effective at preventing new COVID-19 infections, with few side effects, questions remain about how long the immunity will last.

The key will be taking steps to work with community leaders and health officials to build trust and educate the public on what to expect in terms of vaccine safety and effectiveness, Yamey and others said.

Dec. 3 (UPI) -- The effectiveness of new vaccines developed to prevent COVID-19 likely depends on how well they are distributed and the degree to which the public is willing to take them, public health experts from Johns Hopkins University and Duke University said Thursday.

More than 80% of the Pfizer and Moderna vaccine doses "have already been purchased by rich nations," Yamey, professor of practice, global health and public policy at Duke, said during a call with reporters Thursday.

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Image of article 'Even the Pandemic Hasn’t Made Public-Health Icon Paul Farmer Lose Hope'

Even the Pandemic Hasn’t Made Public-Health Icon Paul Farmer Lose Hope

Even with a teaching load at Harvard, a job as the chief of global health equity at Boston’s Brigham and Women’s Hospital and the Massachusetts contact-tracing gig, this year has been a slow one for Farmer, a man who typically spends a good chunk of his time on different continents.

PIH was well positioned to help when COVID-19 arrived in the U.S., given its experience in places similarly lacking staff, space, stuff and systems.

The book details PIH’s work during the crisis, but Farmer insists it was mainly intended as a “reparative exercise”—one inspired by patients who survived Ebola, and meant to elevate West African voices, experiences and histories.

Since then, PIH and its global staff of 18,000 have helped strengthen health systems in the “clinical deserts” of Haiti, Rwanda, Peru, Russia and numerous other countries.

Image of article 'Introducing Healthcare Docket'

Introducing Healthcare Docket

The coronavirus pandemic has raised myriad legal complexities in the healthcare and life sciences sectors.

To address the need for sophisticated news and analysis in this environment, Breaking Media is launching Healthcare Docket, a new newsletter drawing on its leading publications in the healthcare (MedCity News) and legal (Above the Law) industries.

Distributed weekly, Healthcare Docket will serve an audience that includes in-house counsel throughout the U.S. healthcare sector, including health systems, life sciences companies, and technology firms with ambitions in healthcare.

Please email advertising@breakingmedia.com for Healthcare Docket sponsorship opportunities.

The newsletter features regulatory developments and litigation affecting the healthcare sector, as well as technological advances, mergers and other transactions, major intellectual property rulings, and broad industry trends.

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Italy Fines Apple $12 Million For Unfair Claims About iPhone Water Resistance

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UK Becomes the First Country To Approve Pfizer/BioNTech Coronavirus Vaccine, Roll Out To Start Next Week

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Slashdot Apparel is back!

You can keep using GitHub but automatically sync your GitHub releases to SourceForge quickly and easily with this tool and take advantage of SourceForge's massive reach.

Check out all of SourceForge’s improvements.

| Follow Slashdot on LinkedIn

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