AbbVie's upadacitinib successful in third late-stage dermatitis study (NYSE:ABBV

published 28.07.2020 11:20

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AbbVie (NYSE:ABBV) announces another successful Phase 3 clinical trial, AD Up, evaluating Rinvoq (upadacitinib) plus topical corticosteroids (TCS) in adults and adolescents with moderate-to-severe atopic dermatitis.

Specifically, 77% of patients receiving 30 mg of upadacitinib plus TCS achieved EASI 75 (75% improvement in EASI score) compared to 26% in the placebo arm.

59% of patients in the cohort achieved clear or almost clear skin compared to 11% in the control arm.

64% experienced at least a four-grade improvement in itchy skin compared to 15% in the control arm.

Two previous Phase 3s, MEASURE Up 1 & MEASURE Up 2, were also successful.

by Douglas W. House from

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